Welfare reforms could push many disabled people into poverty, a disabled rights organisation says.
The UK government has proposed changes to disability benefits that it is expected will require recipients reassessed.
Disability Wales told BBC1's Politics Show it was "inevitable" many would face a loss of income.
The Department for Work and Pensions said the reassessment process would be fair.
The UK Government has suggested making changes to the disability living allowance, mobility payments and independent living fund.
Changes to housing benefits and the introduction of universal credits are also on the way.
Paul Swann, independent living officer for Disability Wales, told the programme that the proposed changes would leave disabled people "marginalised".
"Inevitably there's going to be a loss of income for virtually every disabled person," he said.
"The consequences of that for many disabled people is that they're going to be pushed into poverty and the impact is that disabled people are going to be more and more marginalised, more and more excluded from society than they are now".
“Start Quote
"I think there's a lot of unnecessary worry, we don't know half of the detail yet”
End Quote Karen RObson Disability officer, Uwic
Although the exact details of the welfare changes are not yet known, it is widely expected that all people with disabilities in receipt of benefits will have to undergo a reassessment of their needs.
Disability Wales is concerned that too much emphasis will be placed on whether people are physically fit to work.
Mr Swann said: "The reassessment process is fundamentally flawed by only looking at people's impairments and very often prioritising their physical impairments and not giving due value to other impacts such as social exclusion and so on".
The Department for Work and Pensions (DWP) said the reassessment process would be be fair and was necessary to "find out what individuals are capable of doing, rather than focus on what they can't do".
However, Karen Robson, disability officer at the University of Wales Institute, Cardiff (Uwic), said changing the assessment process may actually help.
"It's about a simplification of the benefits system," she said.
'Unnecessary worry'
"I used to work for the Citizens Advice Bureau and when it comes to the benefits system there are a lot of benefits that go unclaimed because it's so complicated to work your way through the process so I would hope that the systems we put in place will make it easier to get through the process".
Ms Robson said that people with disabilities should wait for the details before worrying.
"I think there's a lot of unnecessary worry, we don't know half of the detail yet.
"I know there are a lot of changes that people are very worried about those but I think it's really important that we keep a level of perspective about this.
"Everyone is experiencing cuts right across the board, I don't believe disabled people are being singled out for particular pain."
PDF version The 2011 edition of indicators of poverty and social exclusion in Wales, providing a comprehensive analysis of trends.
This is the third update of Monitoring poverty and social exclusion in Wales. It is set against the Welsh Government's stated commitment to end child poverty by 2020. After looking at the mixed results of policy over the last ten years, it examines how far higher employment might take Wales towards its goal - and what its wider implications might be.
The study examines:
- Poverty rates amongst adults, children and pensioners;
- Under-employment;
- Qualification levels;
- The effects of higher employment on child poverty.
Mae'r cyhoeddiad hwn hefyd ar gael yn Gymraeg (PDF, 283KB).
Welfare changes will see 60,000 people in Wales moved off incapacity benefits, with half leaving the benefits system with no jobs to go to, research claims.
The report for councils suggests a £100m job creation scheme for 20,000 by the Welsh Government to plug the gap.
The Welsh Government says it is committed to a new employment programme for young people.
The UK government's Department for Work and Pensions said it would not leave anyone "trapped on benefits".
The Sheffield Hallam University report by Prof Steve Fothergill and Christina Beatty will form part of discussions at a conference on the employment prospects for the valleys in Merthyr Tydfil on Tuesday.
It was commissioned by the Industrial Communities Alliance, which represents councils in some of the most deprived areas in Wales.
The research claims that the UK government's welfare change programme will not help get more people in Wales into work unless there is a significant increase in the number of job opportunities.
http://www.bbc.co.uk/news/uk-wales-14016177